Amino Acid Products Shortage

• • Aminosyn II (sulfite-free) injection, ICU Medical, 10%, 2000 mL flexible container, 6 count, NDC 00990-7172-17
  • Aminosyn II (sulfite-free) injection, ICU Medical, 15%, 2000 mL flexible container, 6 count, NDC 00990-7171-17
  • Aminosyn-PF (sulfite-free) injection, ICU Medical, 10%, 1000 mL flexible container, 6 count, NDC 00990-4179-05
  • Aminosyn-PF (sulfite-free) injection, ICU Medical, 7%, 500 mL flexible container, 12 count, NDC 00990-4178-03
  • Plenamine injection, BBraun, 15%, 1000 mL flexible container, 8 count, NDC 00264-4500-00
  • Plenamine injection, BBraun, 15%, 2000 mL flexible container, 8 count, NDC 00264-4500-05
  • Premasol (sulfite-free) injection, Baxter, 10%, 1000 mL flexible container, 12 count, NDC 00338-1130-04
  • Premasol (sulfite-free) injection, Baxter, 10%, 2000 mL flexible container, 6 count, NDC 00338-1130-06
  • Premasol (sulfite-free) injection, Baxter, 10%, 500 mL flexible container, 24 count, NDC 00338-1130-03
  • Travasol injection, Baxter, 10%, 1000 mL flexible container, 12 count, NDC 00338-0644-04
  • Travasol injection, Baxter, 10%, 2000 mL flexible container, NDC 00338-0644-06
  • Travasol injection, Baxter, 10%, 500 mL flexible container, 6 count, NDC 00338-0644-03
  • TrophAmine injection, BBraun, 10%, 500 mL plastic container, 12 count, NDC 00264-1933-10

• • Baxter has some amino acid presentations on shortage due to increased demand.
  • BBraun did not provide a reason for the shortage.
  • ICU Medical has Aminosyn on shortage due to manufacturing delays and shortage of an active ingredient.

• • Clinisol (sulfite-free) injection, Baxter, 15%, 2000 mL flexible container, 6 count, NDC 00338-0502-06
  • Clinisol (sulfite-free) injection, Baxter, 15%, 500 mL flexible container, 24 count, NDC 00338-0502-03
  • Prosol (sulfite-free) injection, Baxter, 20%, 2000 mL flexible container, 6 count, NDC 00338-0499-06

Estimated Resupply Dates

• • Baxter has Premasol 10% 500 mL, 1,000 mL, and 2,000 mL flexible containers on allocation. Travasol 10% 500 mL is also on allocation. Travasol 10% 1,000 mL is in limited supply.
  • BBraun has Trophamine and Plenamine on allocation.
  • ICU Medical has Aminosyn II 10% 2,000 mL, 15% 2,000 mL flexible containers, 7% Aminosyn-PF in 500 mL, and 10% Aminosyn-PF in 1,000 mL containers are on back order and the company cannot estimate a release date.

Implications for Patient Care

• • Travasol product information now includes dosage information for pediatric patients. Travasol product information can be found at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8543b5be-0f43-4891-9e56-d7c39fe839b5. A comparison chart of Premasol and Travasol is available at https://www.nutritioncare.org/uploadedFiles/Documents/Guidelines_and_Clinical_Resources/Comparison%20Chart%20of%20Premasol%20and%20Travasol.pdf

Safety

• • ASPEN provides recommendations for managing shortages of parenteral nutrition products. See their website for more details.