Otezla Interactions
There are 110 drugs known to interact with Otezla (apremilast), along with 3 disease interactions. Of the total drug interactions, 15 are major, 93 are moderate, and 2 are minor.
- View all 110 medications that may interact with Otezla
- View Otezla disease interactions (3)
Most frequently checked interactions
View interaction reports for Otezla (apremilast) and the medicines listed below.
- albuterol
- amlodipine
- aspirin
- atorvastatin
- bupropion
- clobetasol topical
- cyclobenzaprine
- Cymbalta (duloxetine)
- duloxetine
- folic acid
- gabapentin
- hydrochlorothiazide
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- meloxicam
- metformin
- methotrexate
- metoprolol
- omeprazole
- pantoprazole
- prednisone
- rosuvastatin
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Otezla disease interactions
There are 3 disease interactions with Otezla (apremilast) which include:
Report options
More about Otezla (apremilast)
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- Reviews (440)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: antirheumatics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
