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NK1 receptor antagonists

What are NK1 receptor antagonists?

Neurokinin-1 (NK1) receptor antagonists are used for prevention of acute and delayed nausea and vomiting. The NK1 receptor antagonist competitively binds to the NK1 receptor, which blocks the binding of substance P and prevents the emetic signal being transmitted. NK1 receptor antagonists can be used in conjunction with 5-HT3-receptor antagonists and corticosteroids to augment their antiemetic activity.

List of NK1 receptor antagonists

View by  Generic | Brand
Drug Name Avg. Rating Reviews
aprepitant systemic (Pro)
Brand names: Aponvie, Cinvanti, Emend
8.0
 18 reviews
rolapitant systemic (Pro)
Brand name: Varubi
10
 1 review
fosaprepitant systemic (Pro)
Brand names: Emend for Injection, Focinvez
8.0
 1 review
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with NK1 receptor antagonists:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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